Capixyl (Acetyl Tetrapeptide-3 & Red Clover Flower Extract)

Capixyl is a patented ingredient complex developed by Lucas Meyer Cosmetics that brings together two distinct actives: Acetyl Tetrapeptide-3, a synthetic peptide designed to strengthen the follicle anchoring environment, and red clover flower extract, a botanical source of biochanin A, an isoflavone studied for its role in managing DHT at the follicle level.

The two components address hair thinning and loss through complementary mechanisms, one structural and one hormonal, which is the basis for Capixyl's reputation as one of the more clinically substantiated complexes in modern scalp care.

At Arey, Capixyl is a key active in Good Night, Grey®, our overnight scalp serum, where it works during the body's natural repair cycle to support a stronger, denser hair environment.

Hair loss and thinning happen through multiple pathways. Capixyl targets two of the most significant.

Acetyl Tetrapeptide-3 works at the level of the extracellular matrix, the structural proteins, including laminin and collagen, that form the dermal-epidermal junction and anchor the hair follicle in the scalp. Research has shown that the peptide stimulates the synthesis of these proteins, strengthening the follicle's physical hold in the scalp and helping to counteract the structural weakening that contributes to hair thinning over time. It has also been studied for its ability to stimulate proliferation of the dermal papilla cells that regulate the hair growth cycle.

Red Clover Flower Extract contributes biochanin A, an isoflavone that has been studied as a natural inhibitor of 5-alpha reductase, the enzyme responsible for converting testosterone into DHT. Because DHT is one of the primary drivers of genetic hair thinning and follicle miniaturization, reducing its activity at the follicle level is a meaningful intervention for people experiencing hormonally driven hair loss. Biochanin A provides this effect through a botanical pathway rather than a pharmaceutical one.

In clinical studies on the combined Capixyl complex, the two actives together demonstrated a measurable reduction in hair loss and an improvement in hair density with consistent use, results that neither component has been shown to achieve as effectively in isolation.

Hair thinning and grey hair are not unrelated problems. Both reflect changes happening inside the follicle over time, and both respond to the same principle: the follicle environment needs consistent, targeted support to maintain its function. Capixyl addresses the structural and hormonal drivers of thinning that often accompany the onset of grey, which is why it belongs in the same product.

We include Capixyl specifically in Good Night, Grey® because overnight is when the body's natural repair processes are most active. Applying a complex that strengthens follicle anchoring proteins and reduces DHT activity during that window gives it the best conditions to work. It is one of the reasons Good Night, Grey® is more than a pigmentation serum.